Lindera aggregata

Lindera aggregata
Scientific classification
Kingdom:	Plantae
Clade:	Tracheophytes
Clade:	Angiosperms
Clade:	Magnoliids
Order:	Laurales
Family:	Lauraceae
Genus:	Lindera
Species:	L. aggregata
Binomial name
	Lindera aggregata; (Sims) Kosterm.

Lindera aggregata is a plant species belonging to the genus Lindera.

Other names

Engl.: evergreen lindera, Japanese evergreen spicebush.
TCM: trad.烏藥, simpl. 乌药 or 乌乐, pinyin : wūyào.
Bot. syn.: Benzoin strychnifolium (Sieb. & Zucc.) Kuntze, Daphnidium strychnifolium Sieb. & Zucc., Laurus aggregata Sims, Lindera eberhardtii Lecomte, Lindera strychnifolia (Sieb. & Zucc.) Fern.

Use

乌药, radix lindera, is present in the Compendium of Materia Medica and Kampo herb list. It is an ingredient in the traditional Chinese medicine pill Chaihu Shugan Wan against "stagnation of liver qi, distension of chest and hypochondria, indigestion, and acid eructation", and in the Lindera Combination Teapills (simpl. 天台乌药丸, trad. 天臺烏藥丸, pinyin : tiāntái wūyào wán), a Chinese classic herbal formula.

Biochemistry

An A type proanthocyanidin trimer (epicatechin-(4β→8,2β→O→7)-entcatechin-(4β-8)-catechin) can be found in Lindera aggregata.^[1] In a study this compound showed cytoprotective action against ethanol-induced gastric injury in Sprague-Dawley rats.^[2]

Four alkaloids (boldine, norboldine, reticuline and linderegatine) can also be found in L. aggregata.^[3]

References

^ Feng, Z. C.; Shi, S. Q.; Tao, W. Z.; Hattori, M. (2003). "One New A-type Proanthocyanidin Trimer from Lindera aggregata (Sims) Kosterm" (PDF). Chinese Chemical Letters. 14 (10): 1033–1036. Archived from the original (PDF) on 2011-07-07.
^ Zhu, M.; Luk, C. T.; Lew, T. H. (1998). "Cytoprotective Effect of Lindera aggregata Roots Against Ethanol-Induced Acute Gastric Injury". Pharmaceutical Biology. 36 (3): 222–226. doi:10.1076/phbi.36.3.222.6349.
^ Han, Z.; Zheng, Y.; Chen, N.; Luan, L.; Zhou, C.; Gan, L.; Wu, Y. (2008). "Simultaneous determination of four alkaloids in Lindera aggregata by ultra-high-pressure liquid chromatography–tandem mass spectrometry". Journal of Chromatography A. 1212 (1–2): 76–81. doi:10.1016/j.chroma.2008.10.017. PMID 18951552.

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[1] Feng, Z. C.; Shi, S. Q.; Tao, W. Z.; Hattori, M. (2003). "One New A-type Proanthocyanidin Trimer from Lindera aggregata (Sims) Kosterm" (PDF). Chinese Chemical Letters. 14 (10): 1033–1036. Archived from the original (PDF) on 2011-07-07.

[2] Zhu, M.; Luk, C. T.; Lew, T. H. (1998). "Cytoprotective Effect of Lindera aggregata Roots Against Ethanol-Induced Acute Gastric Injury". Pharmaceutical Biology. 36 (3): 222–226. doi:10.1076/phbi.36.3.222.6349.

[3] Han, Z.; Zheng, Y.; Chen, N.; Luan, L.; Zhou, C.; Gan, L.; Wu, Y. (2008). "Simultaneous determination of four alkaloids in Lindera aggregata by ultra-high-pressure liquid chromatography–tandem mass spectrometry". Journal of Chromatography A. 1212 (1–2): 76–81. doi:10.1016/j.chroma.2008.10.017. PMID 18951552.

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