Hydroxycorticosteroids

Hydroxycorticosteroids (OHCSs) are corticosteroids that have an additional hydroxy (-OH) group.

Steroid skeleton. Carbons 18 and above can be absent.

There are two main positions where the hydroxy group may be added: at carbon atom 11, and at carbon atom 17.

At the 11 position

Corticosterone (an 11-hydroxycorticosteroid).

11-hydroxycorticosteroids (11-OHCSs) include:

• aldosterone
• corticosterone
• hydrocortisone

At the 17 position

Cortisone (a 17-hydroxycorticosteroid).

17-hydroxycorticosteroids (17-OHCSs) include:

• cortisone
• hydrocortisone

External links

• MedlinePlus Encyclopedia: 003459