2-Deoxystreptamine glucosyltransferase
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2-deoxystreptamine glucosyltransferase (EC 2.4.1.284, kanF (gene)) is an enzyme with systematic name UDP-alpha-D-glucose:2-deoxystreptamine 6-alpha-D-glucosyltransferase.[1] This enzyme catalyses the following chemical reaction
2-deoxystreptamine glucosyltransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.4.1.284 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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- UDP-alpha-D-glucose + 2-deoxystreptamine UDP + 2'-deamino-2'-hydroxyparomamine
This enzyme is involved in the biosynthesis of kanamycin B and kanamycin C.
References
edit- ^ Park JW, Park SR, Nepal KK, Han AR, Ban YH, Yoo YJ, Kim EJ, Kim EM, Kim D, Sohng JK, Yoon YJ (October 2011). "Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation". Nature Chemical Biology. 7 (11): 843–52. doi:10.1038/nchembio.671. PMID 21983602.
External links
edit- 2-deoxystreptamine+glucosyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)