2-Formylbenzoate dehydrogenase (EC 1.2.1.78, 2-carboxybenzaldehyde dehydrogenase, 2CBAL dehydrogenase, PhdK) is an enzyme with systematic name 2-formylbenzoate:NAD+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction
| 2-Formylbenzoate dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.2.1.78 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- 2-formylbenzoate + NAD+ + H2O o-phthalic acid + NADH + H+
The enzyme is involved in phenanthrene degradation.
References
edit- ^ Iwabuchi T, Harayama S (October 1997). "Biochemical and genetic characterization of 2-carboxybenzaldehyde dehydrogenase, an enzyme involved in phenanthrene degradation by Nocardioides sp. strain KP7". Journal of Bacteriology. 179 (20): 6488–94. PMC 179567. PMID 9335300.
- ^ Kiyohara H, Nagao K, Yano K (1981). "Isolation and some properties of NAD-linked 2-carboxybenzaldehyde dehydrogenase in Alcaligenes faecalis AFK 2 grown on phenanthrene". J. Gen. Appl. Microbiol. 27: 443–455. doi:10.2323/jgam.27.443.
External links
edit- 2-formylbenzoate+dehydrogenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
