6-Nitroquipazine (developmental code name DU-24,565) is a potent and selective serotonin reuptake inhibitor used in scientific research.[1][2]
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| Formula | C13H14N4O2 |
| Molar mass | 258.281 g·mol−1 |
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6-Nitroquipazine has been found to inhibit melanogenesis in-vitro,[3] suggesting that it can be used for skin whitening.
See also
editReferences
edit- ^ Vaatstra WJ, Deiman-Van Aalst WM, Eigeman L (March 1981). "Du 24565, a quipazine derivative, a potent selective serotonin uptake inhibitor". European Journal of Pharmacology. 70 (2): 195–202. doi:10.1016/0014-2999(81)90214-4. PMID 6973481.
- ^ Classen K, Göthert M, Schlicker E (June 1984). "Effects of DU 24565 (6-nitroquipazine) on serotoninergic and noradrenergic neurones of the rat brain and comparison with the effects of quipazine". Naunyn-Schmiedeberg's Archives of Pharmacology. 326 (3): 198–202. doi:10.1007/bf00505318. PMID 6206407. S2CID 20858707.
- ^ McEwan M, Parsons PG (July 1987). "Inhibition of melanization in human melanoma cells by a serotonin uptake inhibitor". The Journal of Investigative Dermatology. 89 (1): 82–86. doi:10.1111/1523-1747.ep12580425. PMID 3110297. No-cost access but non-free license.