8C or VIII-C may refer to:
- Alfa Romeo 8C and the unrelated Alfa Romeo 8C Competizione
- Maserati 8C, a 1932 Grand Prix race car
- Stalag VIII-C, a World War II German POW camp near Sagan
- Carbon-8 (8C), an isotope of carbon
- Air Transport International, IATA code
- Eighth Cambridge Survey (8C)
- Shanxi Airlines, IATA code
- Cotai Water Jet, IATA code