An Activin receptor is a receptor which binds activin. These proteins are receptor-type kinases of Ser/Thr type, which have a single transmembrane domain and a specific hydrophilic Cys-rich ligand-binding domain.[1][2][3]
| Activin types I and II receptor domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Activin_recp | ||||||||
| Pfam | PF01064 | ||||||||
| InterPro | IPR000472 | ||||||||
| PROSITE | PDOC00223 | ||||||||
| SCOP2 | 1tbi / SCOPe / SUPFAM | ||||||||
| Membranome | 1216 | ||||||||
| |||||||||
Types include:
Human proteins containing this domain
editACVR1; ACVR1B; ACVR1C; ACVR2A; ACVR2B; ACVRL1; BMPR1A; BMPR1B; BMPR2; TGFBR1;
References
edit- ^ Wrana JL, Attisano L (1996). "Signal transduction by members of the transforming growth factor-beta superfamily". Cytokine Growth Factor Rev. 7 (4): 327–339. doi:10.1016/S1359-6101(96)00042-1. PMID 9023056.
- ^ Wrana JL, Attisano L, Wieser R, Ventura F, Massague J (1994). "Mechanism of activation of the TGF-beta receptor". Nature. 370 (6488): 341–347. doi:10.1038/370341a0. PMID 8047140. S2CID 4344481.
- ^ Massague J, Weis-Garcia F (1996). "Serine/threonine kinase receptors: mediators of transforming growth factor beta family signals". Cancer Surv. 27: 41–64. PMID 8909794.
External links
edit- Activin+receptors at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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