Polyostotic fibrous dysplasia is a form of fibrous dysplasia affecting more than one bone.[2] Fibrous dysplasia is a disorder where bone is replaced by fibrous tissue, leading to weak bones, uneven growth, and deformity. [3]
| Polyostotic fibrous dysplasia | |
|---|---|
| Other names | Albright's disease[1]: 578 |
| Specialty | Osteology |
McCune–Albright syndrome includes polyostotic fibrous dysplasia as part of its presentation.[4] When polyostotic fibrous dysplasia manifests in the long bones, limping results; when it manifests in the face, asymmetric growth of the face can result.[3]
One treatment that has been used is bisphosphonates.[5]
See also
editReferences
edit- ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
- ^ "Fibrous Dysplasia: Overview - eMedicine Radiology". Retrieved 2009-02-23.
- ^ a b Reference, Genetics Home. "McCune–Albright syndrome". Genetics Home Reference. Retrieved 2018-10-30.
- ^ Lee, Peter A. (5 December 1986). "McCune–Albright Syndrome: Long-term Follow-up". JAMA: The Journal of the American Medical Association. 256 (21): 2980–4. doi:10.1001/jama.1986.03380210076028. PMID 3773215.
- ^ Khadilkar VV, Khadilkar AV, Maskati GB (September 2003). "Oral bisphosphonates in polyostotic fibrous dysplasia". Indian Pediatr. 40 (9): 894–6. PMID 14530553.
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