The medical condition pseudopelade of Brocq is a flesh- to pink-colored, irregularly shaped alopecia that may begin in a moth-eaten pattern with eventual coalescence into larger patches of alopecia.[1]: 648 [2]: 761
| Pseudopelade of Brocq | |
|---|---|
| Other names | Alopecia cicatrisata |
| Specialty | Dermatology |
Signs and symptoms
editThe most typical location for the first lesion is the vertex. The eyebrows and beard may be impacted. There are sporadic yet distinct alopecia confluent areas that resemble snow footprints. In the early stages, there is minor perifollicular erythema, and in the later stages, there is significant atrophy.[3]
Pseudopelade lesions are spaced haphazardly. It typically manifests as an atrophic plaque that is porcelain white, hypopigmented, and somewhat depressed. Instead of the typical round or oval patches associated with alopecia areata, lesions are frequently uneven in shape.[4]
Causes
editThe pathogenesis of pseudopelade of Brocq is still not well understood. A number of potential contributing variables include senescence of the follicular stem cell reserve, acquired autoimmunity, and Borrelia infection.[3] The pathophysiology of familial pseudopelade of Brocq may be influenced by heredofamilial variables, according to a small number of case reports and case series.[5]
Diagnosis
editPseudopelade of Brocq is identified using clinical and trichoscopy exclusion. There are two types of pseudopelade of Brocq, primary and secondary.[3]
Treatment
editThe progression of the disease eventually terminates on its own. There is no accepted course of care.[4]
See also
editReferences
edit- ^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
- ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
- ^ a b c Nair, PragyaAshok; Singhal, Rochit; Pariath, Kira (2017). "Primary idiopathic pseudopelade of brocq in a young child". International Journal of Trichology. 9 (3). Medknow: 113. doi:10.4103/ijt.ijt_24_17. ISSN 0974-7753. PMC 5596645.
- ^ a b Nair, PragyaA; Diwan, Nilofar; Gohil, Sneha (2014). "Primary idiopathic pseudopelade of brocq: Five case reports". International Journal of Trichology. 6 (1). Medknow: 27. doi:10.4103/0974-7753.136759. ISSN 0974-7753. PMC 4124692.
- ^ (HM), Scientific Scholar; Sharma, DK; Pandey, SS (1993-06-30). "Familial incidence of pseudopelade of brocq". Indian Journal of Dermatology, Venereology and Leprology. 59. scientific scholar. ISSN 0378-6323. Retrieved 2024-03-26.
Further reading
edit- Amato, L.; Massi, D.; Berti, S.; Moretti, S.; Fabbri, P. (2002). "A multiparametric approach is essential to define different clinicopathological entities within pseudopelade of Brocq". British Journal of Dermatology. 146 (3). Oxford University Press (OUP): 532–532. doi:10.1046/j.1365-2133.2002.46527.x. ISSN 0007-0963.
- COLLIER, P.M.; JAMES, M.P. (1994). "Pseudopelade of Brocq occurring in two brothers in childhood". Clinical and Experimental Dermatology. 19 (1). Oxford University Press (OUP): 61–64. doi:10.1111/j.1365-2230.1994.tb01119.x. ISSN 0307-6938.