Andrea Califano is an American biologist. He is a Clyde and Helen Wu professor of Chemical and Systems Biology at Columbia University Irving Medical Center. He also has roles in the Departments of Biochemistry & Molecular Biophysics, Biomedical Informatics, and Medicine.
Education and career
editCalifano earned his Ph.D. in physics from the University of Florence, Italy, in 1986. He then joined the IBM T.J. Watson Research Center,[1] where he became the program director of the IBM Computational Biology Center in 1997. He joined Columbia University in 2003.[2]
Califano serves on various editorial and scientific advisory boards, including the Board of Scientific Advisors of the National Cancer Institute,[3] St. Jude Children's Hospital, Koch Institute for Integrative Cancer Research,[4] and Thermo Fisher Scientific Inc..[5] He is also the co-founder and Chief Scientific Advisor of DarwinHealth.[6]
Research work
editCalifano is renowned for his work in reverse engineering gene regulatory networks and analyzing them to identify key tumor checkpoint modules.[7] This research has led to several clinical trials, including an N-of-1 study that analyzes patients with 14 untreatable, lethal cancers individually to prioritize therapeutic strategies.[8]
Honors and awards (selected)
edit- NCI Outstanding Investigator Award (R35) in 2015[9] and 2022[10]
- AAAS Fellow (2015)[11]
- ISCB Fellow (2017)[12]
- Member of the National Academy of Medicine (2018)[13]
- 2019 Ruth Leff prize in pancreatic cancer research[14]
- 2023 Alfred G. Knudson prize in Cancer Genetics.[15]
- Fellow of the AACR Academy (2024)[16]
References
edit- ^ "Technology: Searching for DNA sequences in a flash". New Scientist.
- ^ "Faculty Details | Columbia University Department of Systems Biology". Columbia.edu.
- ^ "Andrea Califano Appointed to the NCI Board of Scientific Advisors | Columbia University Department of Systems Biology". Columbia.edu.
- ^ "Scientific Advisory Board". Koch Institute.
- ^ "Thermo Fisher Scientific Appoints New Members To Scientific Advisory Board". BioSpace. 16 September 2014.
- ^ "Computing cancer's weak spots". Science.org.
- ^ "Ongoing Research in Early-Stage Invasive Breast Cancer Treatment - Advances for Medical Professionals". NewYork-Presbyterian.
- ^ "Targeting Cancer's Hidden Masters". Columbia University Irving Medical Center. 13 October 2023.
- ^ "Andrea Califano Named NCI Outstanding Investigator | Columbia University Department of Systems Biology". Columbia.edu.
- ^ "2022 NCI Outstanding Investigator Award Recipients - NCI". Cancer.gov. 2 November 2022.
- ^ "2015 AAAS Fellows Recognized for Contributions to Advancing Science | American Association for the Advancement of Science (AAAS)". AAAS.org.
- ^ "ISCB Fellows". ISCB.
- ^ "National Academy of Medicine Elects 85 New Members". Nam.edu.
- ^ "Ruth Leff Siegel Award Winners | Columbia Surgery". Columbia University.
- ^ "Andrea Califano Receives Alfred G. Knudson Award from NCI". Columbia University. 16 October 2023.
- ^ "Class of 2024". American Association for Cancer Research (AACR).
External links
edit- Andrea Califano publications indexed by Google Scholar