Andrew Fyfe may refer to:
- Andrew Fyfe (cartoonist) (born 1966), Australian cartoonist and satirist
- Andrew Fyfe (chemist) (1792–1861), Scottish surgeon and chemist
- Andrew Fyfe the Elder (1754–1824), his father, Scottish anatomist
- Andy Fyfe (born 1913), Scottish footballer (Kilmarnock FC, Greenock Morton)
- Andy Fyfe (footballer, born 1898), Scottish footballer