Antonio Esposito may refer to:
- Antonio Esposito (footballer, born 1972), Swiss-Italian former midfielder
- Antonio Esposito (footballer, born 1983), Italian midfielder
- Antonio Esposito (footballer, born 1990), Italian midfielder
- Antonio Esposito (footballer, born 2000), Italian fullback
- Antonio Esposito (judoka), born 1994, Italian judoka
- Tony Esposito (musician), born 1950, Italian singer and songwriter