Azaryan or Azarian (Armenian: Ազարյան) is an Armenian and Persian surname. Notable people with the surname include:
- Albert Azaryan (born 1929), Soviet Armenian artistic gymnast
- Eduard Azaryan (born 1958), Soviet Armenian artistic gymnast
- Krikor Azaryan (1934–2009), Bulgarian theatre director
- Mary Azarian (born 1940), American woodcut artist and children's book illustrator
- Mihran Azaryan (1876–1952), Ottoman Armenian and Turkish architect
- Mina Azarian (born 1959), Swedish actress
- Onnik Der Azarian (1883–1935), Ottoman Armenian painter