Barbarin is a surname. Notable people with the surname include:
- Imani Barbarin (born 1990), American writer and disability rights activist
- Paul Jean Joseph Barbarin (1855–1931), French mathematician
- Philippe Barbarin, Archbishop emeritus of Lyon, France, and Cardinal of the Catholic Church
- Members of the musical Barbarin family
- Isidore Barbarin (1871–1960), New Orleans jazz cornet and alto horn player and bandleader, father of Paul and Louis, grandfather of Danny Barker, great-grandfather of Lucien
- Lucien Barbarin (1956–2020), New Orleans trombone player
- Paul Barbarin (1899–1969), New Orleans jazz drummer
- Louis Barbarin (1902–1997), New Orleans jazz drummer