Franklin High School or Franklin Senior High School may refer to:
- Benjamin Franklin High School (New York City)
- Benjamin Franklin High School (New Orleans)
- Benjamin Franklin High School (Philadelphia)
- Felicity-Franklin High School, Felicity, Ohio
- Franklin High School (Elk Grove, California)
- Franklin High School (Los Angeles, California)
- Franklin High School (Stockton, California)
- Franklin Senior High School (Indiana)
- Franklin High School (Reisterstown, Maryland)
- Franklin High School (Massachusetts)
- Franklin High School (Livonia, Michigan)
- Franklin High School (New Hampshire)
- Franklin High School (New Jersey), in Somerset County
- Franklin High School (Sussex County, New Jersey)
- Franklin High School (North Carolina)
- Franklin High School (Franklin, Ohio)
- Franklin High School (Portland, Oregon)
- Franklin High School (Tennessee)
- Franklin High School (El Paso, Texas)
- Franklin High School (Franklin, Texas)
- Franklin High School (Virginia)
- Franklin High School (Seattle), Washington
- Franklin High School (Wisconsin)