Big Six or Big 6 may refer to:

Art, entertainment, and media

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Business and industry

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Organizations and movements

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  • Big Six (activists), leaders of major organizations in the civil rights movement within the United States in the 1960s
  • The Big Six (Ghana), six Ghanaian nationalists jailed by the British colonial government in 1948

Sports

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Athletes

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  • Big Six, the nickname for Jason Estrada, professional boxer born 1980
  • Big Six, the nickname for Christy Mathewson, a baseball pitcher from 1900 to 1916

Transportation

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See also

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