Business Is Business may refer to:
- Business is business, a French comedy play by Octave Mirbeau.
- Business Is Business (PMD album), 1996
- Business Is Business (Young Thug album), 2023
- Business Is Business (1915 film), an American silent film
- Business Is Business (1971 film), a comedy movie directed by Paul Verhoeven
- Business Is Business (1942 film), a French drama film