Byron Keith Darby (born June 4, 1960) is a former American football defensive end in the National Football League (NFL). He was selected by the Philadelphia Eagles in the fifth round of the 1983 NFL draft. He played college football at USC.

Byron Darby
No. 94, 72
Position:Defensive end
Personal information
Born: (1960-06-04) June 4, 1960 (age 64)
Los Angeles, California, U.S.
Height:6 ft 4 in (1.93 m)
Weight:260 lb (118 kg)
Career information
High school:Inglewood
(Inglewood, California)
College:USC
NFL draft:1983 / round: 5 / pick: 120
Career history
 * Offseason and/or practice squad member only
Career NFL statistics
Sacks:13.5
Stats at Pro Football Reference

Darby also played for the Indianapolis Colts and Detroit Lions.