C22 or C-22 or C.22 may refer to:
- C-22 process, a photographic process
- Boeing C-22, a military version of the Boeing 727-100/200
- HMS C22, a 1909 British C-class submarine
- Aérospatiale C.22, a French target drone
- Sauber C22, a 2003 racing car
- Caldwell 22 (NGC 7662, the Blue Snowball Nebula), a planetary nebula in the constellation Andromeda
- Carbon-22 (C-22 or 22C), an isotope of carbon
- Corydoras cochui, the barredtail corydoras, a freshwater catfish
- Malignant neoplasms of liver and intrahepatic bile ducts ICD-10 code
- Centre Municipal Airport FAA LID
This disambiguation page lists articles associated with the same title formed as a letter–number combination.
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