Calumenin

(Redirected from CALU)

Calumenin is a protein that in humans is encoded by the CALU gene.[5][6]

CALU
Identifiers
AliasesCALU, calumenin
External IDsOMIM: 603420; MGI: 1097158; HomoloGene: 936; GeneCards: CALU; OMA:CALU - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001285412
NM_007594
NM_184053

RefSeq (protein)

NP_001124146
NP_001186600
NP_001186601
NP_001186602
NP_001210

NP_001272341
NP_031620
NP_908942

Location (UCSC)Chr 7: 128.74 – 128.77 MbChr 6: 29.35 – 29.38 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Calumenin (CALU) is a calcium-binding protein localized in the endoplasmic reticulum (ER) and is involved in such ER functions as protein folding and sorting. Calumenin is a member of the EF-hand superfamily in the ER and Golgi apparatus named CERC. CERC is an acronym for its family members Cab-45, reticulocalbin, Erc-55 (RCN2), and calumenin. The CALU gene encodes a deduced 315-amino acid protein containing 6 EF-hand motifs, 1 potential N-glycosylation site, and a C-terminal ER retention signal. The human and mouse CALU proteins are 98% identical. CALU mRNA is ubiquitously expressed in human tissues and maps to 7q32.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000128595Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029767Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Yabe D, Taniwaki M, Nakamura T, Kanazawa N, Tashiro K, Honjo T (Aug 1998). "Human calumenin gene (CALU): cDNA isolation and chromosomal mapping to 7q32". Genomics. 49 (2): 331–3. doi:10.1006/geno.1998.5245. PMID 9598325.
  6. ^ a b "Entrez Gene: CALU calumenin".
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Further reading

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