Calcium/calmodulin-dependent protein kinase type IV is an enzyme that in humans is encoded by the CAMK4 gene.[5]

CAMK4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCAMK4, CaMK IV, CaMK-GR, IV, caMK, calcium/calmodulin-dependent protein kinase IV, calcium/calmodulin dependent protein kinase IV, CaMKIV
External IDsOMIM: 114080; MGI: 88258; HomoloGene: 100780; GeneCards: CAMK4; OMA:CAMK4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001744
NM_001323374
NM_001323375
NM_001323376
NM_001323377

NM_009793

RefSeq (protein)

NP_001310303
NP_001310304
NP_001310305
NP_001310306
NP_001735

NP_033923

Location (UCSC)Chr 5: 111.22 – 111.49 MbChr 18: 33.07 – 33.32 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The product of this gene belongs to the serine/threonine protein kinase cluster, and to the Ca2+/calmodulin-dependent protein kinase (CAMK) group. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons, and male germ cells.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000152495Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038128Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Sikela JM, Law ML, Kao FT, Hartz JA, Wei Q, Hahn WE (Mar 1989). "Chromosomal localization of the human gene for brain Ca2+/calmodulin-dependent protein kinase type IV". Genomics. 4 (1): 21–7. doi:10.1016/0888-7543(89)90309-1. PMID 2536634.
  6. ^ "Entrez Gene: CAMK4 calcium/calmodulin-dependent protein kinase IV".

Further reading

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