CED-5 is an ortholog of the mammalian protein Dock180，which present in the nematode worm C. elegans.,[1] the Drosophila melanogaster ortholog of CED-5 is Myoblast city.[2]
| Cell death abnormality gene 5 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Organism | |||||||
| Symbol | CED-5 | ||||||
| Entrez | 177942 | ||||||
| HomoloGene | 55575 | ||||||
| RefSeq (mRNA) | NM_069537.7 | ||||||
| RefSeq (Prot) | NP_501938.1 | ||||||
| UniProt | G5EEN3 | ||||||
| Other data | |||||||
| Chromosome | IV: 10.48 - 10.49 Mb | ||||||
| |||||||
References
edit- ^ Wu YC, Horvitz HR (April 1998). "C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180". Nature. 392 (6675): 501–4. Bibcode:1998Natur.392..501W. doi:10.1038/33163. PMID 9548255. S2CID 205002377.
- ^ Nolan KM, Barrett K, Lu Y, Hu KQ, Vincent S, Settleman J (November 1998). "Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes". Genes & Development. 12 (21): 3337–42. doi:10.1101/GAD.12.21.3337. PMC 317223. PMID 9808621.