Captain Blood may refer to:
- Captain Blood (novel), by Rafael Sabatini
- Captain Blood (1924 film), based on the Sabatini novel
- Captain Blood (1935 film), based on the Sabatini novel
- Fortunes of Captain Blood, a 1950 film based on the Sabatini novel
- Age of Pirates: Captain Blood, 2011 action-adventure game based on Sabatini's novel
- Captain Blood (1960 film), a French-Italian film based on a novel by a different author
- Captain Blood (video game), 1988, unrelated to the Sabatini novel
- Jack Dyer (1913–2003), Australian rules footballer nicknamed Captain Blood