Carpatho-Ruthenians or Carpathian Ruthenians may refer to:
- inhabitants of the historical region of Carpathian Ruthenia in general
- Carpatho-Ruthenian Slavs, including Carpatho-Ruthenian Rusyns and Ukrainians from Carpathian Ruthenia
- Carpatho-Ruthenian Jews, Jews from Carpathian Ruthenia
- Carpatho-Ruthenian Hungarians, Hungarians from Carpathian Ruthenia