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Chad Mirkin

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Chad Alexander Mirkin (born November 23, 1963) is an American chemist. He is the George B. Rathmann professor of chemistry, professor of medicine, professor of materials science and engineering, professor of biomedical engineering, and professor of chemical and biological engineering, and director of the International Institute for Nanotechnology and Center for Nanofabrication and Molecular Self-Assembly at Northwestern University.[2]

Chad Mirkin
Chad Mirkin with AIC Gold Medal, 2016
Born (1963-11-23) November 23, 1963 (age 60)
Phoenix, Arizona, U.S.
Alma materDickinson College, Pennsylvania State University
AwardsLemelson-MIT Prize, 2009
Linus Pauling Award, 2013
Raymond and Beverly Sackler Prize in Convergence Research, 2015
Dan David Prize, 2016
Wilhelm Exner Medal, 2017
William H. Nichols Medal Award, 2017
Kabiller Prize, 2019
Perkin Medal, 2019
AAAS Philip Hauge Abelson Prize, 2020
King Faisal Prize, 2023
Kavli Prize, 2024
Scientific career
FieldsChemistry, Materials science, and Nanotechnology
InstitutionsNorthwestern University
Notable students
External videos
video icon "Nanotechnology: Moving Beyond Small Thinking", Chad Mirkin, Air Force Office of Scientific Research (AFOSR)

Mirkin is known for his development of nanoparticle-based biodetection schemes, the invention of dip-pen nanolithography (recognized by National Geographic as one of the top 100 scientific discoveries that changed the world), and contributions to supramolecular chemistry, nanoelectronics, and nanooptics. In 2010, he was listed as the most cited chemist in the world over the last decade in terms of total citations, the second highest most cited chemist[3] in terms of impact factor,[4] and the top most cited nanomedicine researcher.[5]

Early life and education

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Mirkin was born November 23, 1963, in Phoenix, Arizona.[6] He received his B.S. degree from Dickinson College in 1986 and his PhD from Penn State University in 1989 under the direction of Professor Gregory L. Geoffroy.[2][7] He was a NSF postdoctoral research fellow at Massachusetts Institute of Technology where he worked with Professor Mark S. Wrighton on microelectrode devices for electrocatalysis.[8] He became a professor at Northwestern University in 1991.[7]

Research

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The focus of Mirkin's research is on developing methods for controlling the architecture of molecules and materials on the 1 – 100 nm length scale and utilizing such structures in the development of analytical tools that can be used in the areas of chemical and biological sensing, lithography, catalysis, and optics. Mirkin has pioneered the use of DNA and nanoparticles as synthons in materials science and the development of nanoparticle-based biodiagnostics.[2][7]

A common strategy used by Mirkin's group is the use of the unique properties of spherical nucleic acids (SNAs), spherical arrangements of nucleic acids with or without organic or inorganic nanoparticle cores, to enable the synthesis of novel materials and colloidal crystals, the development of high sensitivity probes for chemical and medical diagnostic purposes, and single-entity structures capable of intracellular gene regulation. His 1996 work with SNA-gold nanoparticle conjugates introduced the concept of a nanoparticle as an atom and nucleic acids as bonds, and it laid the ground work for the fields of colloidal crystal engineering with DNA and molecular diagnostics based upon well-defined nanoparticle and nanocrystal bioconjugates. SNAs are the cornerstone of Luminex's FDA-cleared Verigene system (now used in over half of the world's top hospitals), EMD Millipore's SmartFlare platform (licensed to AuraSense, Inc.[1] and Holden Pharma), and seven drugs in human clinical trials. In addition, his inventions of DPN, Polymer Pen Lithography (PPL), and Beam Pen Lithography (BPL) are the basis for the TERA-fab M and E series commercial patterning tools, known as desktop fabs (TERA-print, LLC).

He has published over 880 manuscripts, with a Google Scholar H-index of 203,[9] and has over 1,200 patents and patent applications.[10]

Mirkin has been elected into all three branches of the National Academies of Sciences, Engineering, and Medicine, the 10th person so honored.[11] He has served on several editorial advisory boards, including ACS Nano, the Journal of the American Chemical Society and Angewandte Chemie. He is the founding editor of the nanotechnology journal Small, and he is an associate editor of the Journal of the American Chemical Society.[12] Mirkin is a co-founder of multiple companies, including NanoInk,[13] Nanosphere (acquired by Luminex for $83M in 2016 [14]), Azul 3D,[15] TERA-print,[16] Exicure,[17] and Stoicheia.[18]

Information scientists at CAS, a division of the American Chemical Society, singled out Mirkin and his contributions to supramolecular chemistry and nanomaterials in an article about potential future winners of the Nobel Prize in Chemistry, saying that “Overall, Mirkin’s work set up the foundation of modern nanotechnology and development of related diagnostic, therapeutic, and material applications.” [19]

Science policy

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In addition to his academic and research work, Mirkin has been involved in shaping science policy decisions. From 2009 to 2017 Mirkin was appointed to President Barack Obama's President's Council of Advisors on Science and Technology (PCAST).[20][21] He co-chaired the PCAST report titled, "Engage to Excel," focusing on teaching and engagement issues involving students who are in their first two years of undergraduate study at R-1, 2 and 4-year institutions, and community colleges.[22]

Awards and honors

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References

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  1. ^ "Alumni". Mirkin. Retrieved 8 September 2023.
  2. ^ a b c "Chad Mirkin, professor". Northwestern University. Weinberg College of Arts & Sciences. Retrieved 21 January 2015.
  3. ^ "Chad Mirkin". ScienceWatch.com. Thomson Reuters. Retrieved 21 January 2015.
  4. ^ "Top ten chemists: Data provided by Thomson Reuters from its Essential Science Indicators, January 1999 – June 2009". Times Higher Education. 3 December 2009. Retrieved 21 January 2015.
  5. ^ "Laboratory Heads Ranked by Total Citation Score". Nanomedicine Research. Nanomedicine Lab Registry. Retrieved 21 January 2015.
  6. ^ "2010 Mack Award Recipient – Dr. Chad A. Mirkin". OSU Department of Chemistry & Biochemistry. Ohio State University. Archived from the original on 2015-11-19. Retrieved 17 November 2015.
  7. ^ a b c "Chad A. Mirkin". Northwestern University. Mirkin Research Group. Retrieved 21 January 2015.
  8. ^ Mirkin, Chad. "Postdoctoral Research Fellowships in Chemistry Mirkin, Chad". Granthome.
  9. ^ "Google Scholar". Retrieved 20 January 2022.
  10. ^ "Pandemic shows the need for an American manufacturing revival that Chicago could lead". Chicago Sun-Times. July 17, 2020. Retrieved July 27, 2021.
  11. ^ "ACS Award For Creative Invention". Chemical & Engineering News. January 2, 2012. Retrieved 27 July 2021.
  12. ^ "About Chad". Retrieved July 27, 2021.
  13. ^ "NanoInk", Wikipedia, 2019-06-29, retrieved 2020-04-03
  14. ^ "Luminex Buys Nanosphere for $83M", GEN, 2019-05-16, retrieved 2020-05-27
  15. ^ "Azul3D: About Us". Retrieved July 27, 2021.
  16. ^ "TERA-print: Team". Archived from the original on July 27, 2021. Retrieved July 27, 2021.
  17. ^ "Exciure: About Us". Retrieved July 27, 2021.
  18. ^ "Stoicheia: Core Team". Archived from the original on July 27, 2021. Retrieved July 27, 2021.
  19. ^ "Nobel's next nominees? Six impactful discoveries that could be future winners". October 2020. Retrieved October 27, 2020.
  20. ^ Kelleher, Lauren (April 27, 2009). "NU professor named to Obama's science council". The Daily Northwestern. Retrieved 21 January 2015.
  21. ^ Fellman, Megan (April 27, 2009). "Mirkin Named to Obama's Science and Technology Advisory Council". Northwestern University NewsCenter. Retrieved 21 January 2015.
  22. ^ "Report to the President: Engage to Excel: Producing One Million Additional College Graduates with Degrees in Science, Technology, Engineering, and Mathematics" (PDF). February 2012.
  23. ^ "The 2024 Kavli Prize in Nanoscience". www.kavliprize.org. Retrieved 2024-06-14.
  24. ^ "Chad Mirkin – John Simon Guggenheim Memorial Foundation…". Retrieved 2024-06-14.
  25. ^ "King Faisal Prize". kingfaisalprize.org. Retrieved 8 September 2023.
  26. ^ "MRS Medal | Materials Research Society Awards". www.mrs.org. Retrieved 2023-01-31.
  27. ^ "Speaker". IFoRE. Retrieved 2022-11-09.
  28. ^ "World leading engineers win IET Achievement Awards". www.theiet.org. Retrieved 2022-10-21.
  29. ^ https://www.unesco.org/en/articles/innovation-genetic-technologies-rewarded-unesco-equatorial-guinea-international-prize. Retrieved 8 September 2023. {{cite web}}: Missing or empty |title= (help)
  30. ^ "Materials Chemistry open prize: de Gennes Prize". Royal Society of Chemistry. Retrieved 8 September 2023.
  31. ^ "Chad Mirkin to receive Acta Biomaterialia Gold Medal".
  32. ^ "Chad Mirkin to receive G.M. Kosolapoff Award". news.northwestern.edu. Retrieved 8 September 2023.
  33. ^ "Philip Hauge Abelson Prize Recipients | American Association for the Advancement of Science".
  34. ^ "Nanotechnology pioneer Chad Mirkin wins Kabiller Prize in Nanoscience and Nanomedicine".
  35. ^ "SCI Perkin Medal". 31 May 2016.
  36. ^ "The Netherlands Award for Supramolecular Chemistry – FMS Research Center".
  37. ^ "Theodore William Richards Medal Award". Northeastern Section | American Chemical Society. Retrieved 8 September 2023.
  38. ^ "Ira Remsen Award". Maryland Section. 14 November 2018. Archived from the original on 14 November 2018. Retrieved 14 November 2018.
  39. ^ "2 chemists honored with China's Friendship Award". cen.acs.org. Archived from the original on 2020-06-24.
  40. ^ "Mirkin to receive 2018 Harrison Howe Award: Department of Chemistry – Northwestern University".
  41. ^ "提示" (PDF). www.thenanoresearch.com. Retrieved 8 September 2023.
  42. ^ "NY-ACS Nichols Medalists". www.newyorkacs.org. Retrieved 8 September 2023.
  43. ^ University, Carnegie Mellon. "Past Winners - Dickson Prize in Science - Carnegie Mellon University". www.cmu.edu. Retrieved 8 September 2023.
  44. ^ "Dr. Chard Alexander Mirkin". Rusano. 2016. Archived from the original on August 3, 2019. Retrieved January 31, 2017.
  45. ^ "Laureates 2016 | The Dan David Prize". Archived from the original on 2016-03-05.
  46. ^ "American Institute of Chemists Gold Medal". Science History Institute. March 22, 2018.
  47. ^ "Chad A. Mirkin to be Inducted into Medical and Biological Engineering Elite" (PDF). aimbe.org. January 20, 2016. Retrieved 8 September 2023.
  48. ^ "Raymond and Beverly Sackler Prize in Convergence Research".
  49. ^ "Royal Society of Chemistry Prizes and Awards 2015". Royal Society of Chemistry. Retrieved 7 May 2015.
  50. ^ "Vittorio de Nora Award".
  51. ^ "Honorary Professorship on Professor Chad Mirkin from Northwestern University-NanJing Tech University". Archived from the original on 20 November 2020. Retrieved 8 September 2023.
  52. ^ Stoye2013-05-24T00:00:00+01:00, Emma. "Chad Mirkin named Chemistry World Entrepreneur of the Year". Chemistry World. Retrieved 8 September 2023.{{cite web}}: CS1 maint: numeric names: authors list (link)
  53. ^ "Pauling Award Medal 2020".
  54. ^ "NTU and NUS host renowned nanoscience expert and Lee Kuan Yew Distinguished Visitor, Chad Mirkin". Retrieved 8 September 2023.
  55. ^ "News". Archived from the original on 2020-11-16. Retrieved 2020-06-22.
  56. ^ "ACS Award for Creative Invention". Archived from the original on 2020-11-15. Retrieved 2020-06-22.
  57. ^ "Faculty Members Named AAAS Fellows: Northwestern University News". www.northwestern.edu. Retrieved 8 September 2023.
  58. ^ "Northwestern professor Chad Mirkin elected member of the Institute of Medicine". 18 October 2010.
  59. ^ "Chad A. Mirkin". www.nasonline.org. Retrieved 8 September 2023.
  60. ^ "Professor Chad A. Mirkin".
  61. ^ Fellman, Megan (June 24, 2009). "Chad Mirkin Receives $500,000 Lemelson-MIT Prize for Invention". Northwestern University. Retrieved 24 April 2015.
  62. ^ "Penn State's Alumni Fellow Award | Eberly College of Science".
  63. ^ "NIH Director's Pioneer Award Program – 2004 Award Recipients". 18 September 2018.
  64. ^ "Outstanding Science Alumni Award | Eberly College of Science". science.psu.edu. Retrieved 8 September 2023.
  65. ^ "Honorary Degree Recipients | Dickinson College".
  66. ^ "Nobel Laureate Signature Award for Graduate Education in Chemistry".
  67. ^ "The Raymond and Beverly Sackler Prize Previous Years Laureatеs".
  68. ^ "2002 Foresight Institute Feynman Prize". foresight.org. Archived from the original on 2018-06-12.
  69. ^ "Awards | North Jersey Section - American Chemical Society". 9 November 2012.
  70. ^ "George Rathmann Professor: Chad Mirkin". Northwestern. September 2000. Retrieved January 31, 2017.
  71. ^ "ACS Award in Pure Chemistry".
  72. ^ "Chad A. Mirkin – 1992". Novel Discoveries: Beckman Young Investigators, 1991–2009. Irvine, CA: Arnold and Mabel Beckman Foundation. 2011. p. 115.
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