Charles West may refer to:
- Charles Sackville-West, 4th Baron Sackville (1870–1962), British Army general and peer
- Charles West, 5th Baron De La Warr (1626–1687), English nobleman
- Charles Sackville-West, 6th Earl De La Warr (1815–1873), British soldier
- Charles West (actor) (1885–1943), American silent film actor
- Charles West (author) (born 1927), British crime mystery writer and actor
- Charles West (MP), English Member of Parliament for Andover 1678–1679
- Charles West (physician) (1816–1898), founder of London's Great Ormond Street Hospital
- Charles A. West (1890–1957), American basketball and football coach, and college athletics administrator
- Charles Dickinson West (1847–1908), Irish mechanical engineer and naval architect
- Charles F. West (politician) (1895–1955), U.S. Representative from Ohio
- Charles Fremont West (1899–1979), first African American to play quarterback in the Rose Bowl
- Charles P. West (1921–2015), American state politician from Delaware
- Charles S. West (1829–1885), Texas judge and politician
- Major Charles West, son of John West III
- Charlie West (born 1946), American football player
- Charlie West (Australian footballer) (1884–1962), Australian rules footballer
- Charles F. West (aviator) (1899–1972), pioneer aviator