Bazedoxifene/conjugated estrogens

Bazedoxifene/conjugated estrogens
Combination of
Bazedoxifene	Selective estrogen receptor modulator
Conjugated estrogens	Estrogen
Clinical data
Trade names	Duavee, Duavive
AHFS/Drugs.com	Professional Drug Facts
MedlinePlus	a614004
License data	US DailyMed: Duavee;
Pregnancy; category	AU: D; ;
Routes of; administration	By mouth
ATC code	G03CC07 (WHO) ;
Legal status
Legal status	US: ℞-only; EU: Rx-only; In general: ℞ (Prescription only);
Identifiers
CAS Number	1422348-02-4;
ChemSpider	None;
KEGG	D10579;

Bazedoxifene/conjugated estrogens, sold under the brand name Duavee in the US and Duavive in the EU, is a fixed-dose combination medication for the treatment of menopause symptoms and postmenopausal osteoporosis.^[4]^[5]^[6] It contains the selective estrogen receptor modulator bazedoxifene and conjugated estrogens. It is taken by mouth.

The combination was approved for medical use in the United States in October 2013,^[7] and in the European Union in December 2014.^[3]

References

^ "Bazedoxifene / conjugated estrogens (Duavee) Use During Pregnancy". Drugs.com. 16 February 2019. Retrieved 23 June 2020.
^ "Duavee- conjugated estrogens/bazedoxifene tablet, film coated". DailyMed. 16 July 2021. Retrieved 21 February 2022.
^ ^a ^b "Duavive EPAR". European Medicines Agency (EMA). 17 September 2018. Retrieved 10 June 2020.
^ "Duavee. Generic Name: conjugated estrogens and bazedoxifene tablets". rxlist.com.
^ Palacios S, Mejía Ríos A (February 2015). "Bazedoxifene/conjugated estrogens combination for the treatment of the vasomotor symptoms associated with menopause and for prevention of osteoporosis in postmenopausal women". Drugs of Today. 51 (2): 107–16. doi:10.1358/dot.2015.51.2.2281023. PMID 25756066.
^ Lello S, Capozzi A, Scambia G (2017). "The Tissue-Selective Estrogen Complex (Bazedoxifene/Conjugated Estrogens) for the Treatment of Menopause". International Journal of Endocrinology. 2017: 5064725. doi:10.1155/2017/5064725. PMC 5735652. PMID 29358948.
^ "Drug Approval Package: Duavee (conjugated estrogens and bazedoxifene) NDA #022247". U.S. Food and Drug Administration (FDA). 7 October 2013. Retrieved 23 June 2020.

"Bazedoxifene mixture with conjugated estrogens". Drug Information Portal. U.S. National Library of Medicine.

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