Dacuronium bromide (INN, BAN) (developmental code name NB-68) is an aminosteroid neuromuscular blocking agent which was never marketed.[1][2][3][4][5] It acts as a competitive antagonist of the nicotinic acetylcholine receptor (nAChR).[2]
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| Other names | NB-68; 17β-Hydroxypancuronium bromide; 3α-(Acetyloxy)-17β-hydroxy-2β,16β-bis(1-methylpiperidinium-1-yl)-5α-androstane dibromide; 2β,16β-Dipiperidino-5α-androstane-3α,17β-diol 3α-acetate dimethobromide |
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| ECHA InfoCard | 100.043.834 |
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| Formula | C33H58Br2N2O3 |
| Molar mass | 690.646 g·mol−1 |
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References
edit- ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 647–. ISBN 978-1-4757-2085-3.
- ^ a b Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 90–. ISBN 978-94-011-4439-1.
- ^ Progress in Medicinal Chemistry. Elsevier. 1 January 1979. pp. 102–. ISBN 978-0-08-086264-4.
- ^ Maclagan J (1976). "Competitive neuromuscular blocking drugs.". Neuromuscular Junction. Berlin, Heidelberg: Springer. pp. 421–486. ISBN 978-3-642-45476-9.
- ^ Kharkevich DA (6 December 2012). New Neuromuscular Blocking Agents: Basic and Applied Aspects. Springer Science & Business Media. pp. 201–202, 213. ISBN 978-3-642-70682-0.
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