Dave Stapleton may refer to:
- David Stapleton (Lieutenant-General) Irish Defence Forces Chief of Staff 1998–2000
- Dave Stapleton (infielder) (born 1954), baseball player who played with the Boston Red Sox 1980–86
- Dave Stapleton (pitcher) (born 1961), baseball player who played with the Milwaukee Brewers 1987–88
- Dave Stapleton (born 1979), pianist, composer and founder of Edition Records
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