Deane House may refer to:
- in Canada
- Deane House (Fort Calgary), Fort Calgary, Alberta
- in the United States
(by state)
- Deane House (Little Rock, Arkansas), listed on the National Register of Historic Places (NRHP)
- Silas Deane House, Wethersfield, Connecticut, NRHP-listed
- Francis Deane Cottage, Uxbridge, Massachusetts, NRHP-listed
- Deane-Williams House, Cambridge, Massachusetts, NRHP-listed
- Deane House (Cofield, North Carolina), NRHP-listed