Deborah James may refer to:
- Deborah James (activist) (born 1971), American activist
- Deborah James (anthropologist), South African anthropologist
- Deborah James (journalist) (1981–2022), English journalist and podcast host
- Deborah Lee James (born 1958), American public servant who served as the 23rd Secretary of the Air Force
This disambiguation page lists articles about people with the same name.
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