dCMP deaminase (EC 3.5.4.12, deoxycytidylate deaminase, deoxy-CMP-deaminase, deoxycytidylate aminohydrolase, deoxycytidine monophosphate deaminase, deoxycytidine-5'-phosphate deaminase, deoxycytidine-5'-monophosphate aminohydrolase) is an enzyme which converts deoxycytidylic acid to deoxyuridylic acid.[1][2][3]
| dCMP deaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Deoxycytidylate deaminase hexamer, Cyanophage s-tim5 | |||||||||
| Identifiers | |||||||||
| EC no. | 3.5.4.12 | ||||||||
| CAS no. | 9026-92-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
| dCMP deaminase | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | DCTD | ||||||
| NCBI gene | 1635 | ||||||
| HGNC | 2710 | ||||||
| OMIM | 607638 | ||||||
| RefSeq | NM_001921 | ||||||
| UniProt | P32321 | ||||||
| Other data | |||||||
| EC number | 3.5.4.12 | ||||||
| Locus | Chr. 4 q35.1 | ||||||
| |||||||
References
edit- ^ Scarano E (March 1960). "The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. I. The enzymatic deamination of deoxycytidine 5'-phosphate and of 5-methyldeoxycytidine 5-methyldeoxycytidine 5'-phosphate". The Journal of Biological Chemistry. 235 (3): 706–13. doi:10.1016/S0021-9258(19)67927-5. PMID 14442222.
- ^ Scarano E, Bonaduce L (December 1960). "The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. II. Purification and properties of a 6-aminopyrimidine deoxyribonucleoside 5'-phosphate deaminase from unfertilized eggs of sea urchine". The Journal of Biological Chemistry. 235 (12): 3556–61. doi:10.1016/S0021-9258(18)64507-7. PMID 13747062.
- ^ Sergott RC, Debeer LJ, Bessman MJ (December 1971). "On the regulation of a bacterial deoxycytidylate deaminase". The Journal of Biological Chemistry. 246 (24): 7755–8. doi:10.1016/S0021-9258(19)45839-0. PMID 5002683.
External links
edit- dCMP+deaminase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
