Dibenzoxepin

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Dibenzoxepin, or dibenz[b,e]oxepin, is a tricyclic compound. It is the parent structure of certain drugs such as the tricyclic antidepressant doxepin and the analgesic fluradoline.[1][2][3] The former is the only tricyclic antidepressant that is a dibenzoxepin.[3]

Dibenzoxepin
Names
Preferred IUPAC name
Dibenzo[b,e]oxepine
Other names
Dibenz[b,e]oxepin; 9-oxatricyclo[9.4.0.03,8]pentadeca-1,3,5,7,10,12,14-heptaene
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C14H10O/c1-2-7-13-10-15-14-8-4-3-6-12(14)9-11(13)5-1/h1-10H
    Key: APMCUORPNXHBQK-UHFFFAOYSA-N
  • C1=CC=C2C(=C1)C=C3C=CC=CC3=CO2
Properties
C14H10O
Molar mass 194.233 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

See also

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References

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  1. ^ Science of Synthesis: Houben-Weyl Methods of Molecular Transformations Vol. 17: Six-Membered Hetarenes with Two Unlike or More than Two Heteroatoms and Fully Unsaturated Larger-Ring Heterocycles. Thieme. 14 May 2014. pp. 1919–1922. ISBN 978-3-13-178081-2.
  2. ^ Patricia K. Anthony (2002). Pharmacology Secrets. Elsevier Health Sciences. pp. 39–. ISBN 1-56053-470-2.
  3. ^ a b Manuchair Ebadi (31 October 2007). Desk Reference of Clinical Pharmacology, Second Edition. CRC Press. pp. 329–. ISBN 978-1-4200-4744-8.