Diego Castillo may refer to:
- Diego Castillo (swimmer) (born 1991), Panamanian swimmer
- Diego Castillo (pitcher) (born 1994), Dominican baseball pitcher
- Diego Castillo (infielder) (born 1997), Venezuelan baseball infielder
- Diego Castillo (badminton) (born 2001), Chilean badminton player
This disambiguation page lists articles about people with the same name.
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