The DnaX ribosomal frameshifting element is a RNA element found in the mRNA of the dnaX gene in E. coli. The dnaX gene has two encoded products, tau and gamma, which are produced in a 1:1 ratio. The gamma protein is synthesised due to programmed frameshifting and is shorter than tau. The two products of the dnaX gene are DNA polymerase III subunits.[1][2]
| DnaX ribosomal frameshifting element | |
|---|---|
 Predicted secondary structure and sequence conservation of DnaX | |
| Identifiers | |
| Symbol | DnaX |
| Rfam | RF00382 |
| Other data | |
| RNA type | Cis-reg; frameshift_element |
| Domain(s) | Bacteria |
| SO | SO:0005836 |
| PDB structures | PDBe |
References
edit- ^ Larsen B, Gesteland RF, Atkins JF (August 1997). "Structural probing and mutagenic analysis of the stem-loop required for Escherichia coli dnaX ribosomal frameshifting: programmed efficiency of 50%". Journal of Molecular Biology. 271 (1): 47–60. doi:10.1006/jmbi.1997.1162. PMC 7126992. PMID 9300054.
- ^ Blinkova A, Burkart MF, Owens TD, Walker JR (July 1997). "Conservation of the Escherichia coli dnaX programmed ribosomal frameshift signal in Salmonella typhimurium". Journal of Bacteriology. 179 (13): 4438–4442. doi:10.1128/jb.179.13.4438-4442.1997. PMC 179275. PMID 9209069.
External links
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