Douglass High School may refer to:
- Douglass High School (Atlanta, Georgia)
- Douglass High School (Kansas), located in Douglass, Kansas
- Douglass High School (Kingsport, Tennessee), African-American high school closed in 1966
- Douglass High School (Memphis, Tennessee)
- Douglass High School (Webster Groves, Missouri), segregated school that operated from 1926 to 1956
- Douglass High School (Leesburg, Virginia)
Frederick Douglass High School may refer to:
- Frederick Douglass Academy, New York, New York
- Frederick Douglass High School (Baltimore, Maryland)
- Frederick Douglass High School (Columbia, Missouri)
- Frederick Douglass High School (Lexington, Kentucky)
- Frederick Douglass High School (Prince George's County, Maryland)
- Frederick A. Douglass High School (New Orleans), located in New Orleans, Louisiana
- Frederick A. Douglass High School (Oklahoma), located in Oklahoma City, Oklahoma