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Carlotta Guiducci

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Carlotta Guiducci (born 1977) is an Italian bio-engineer. Her research is invested in bio-molecular analysis based on lab-on-a-chip devices. She is an Associate Professor at EPFL (École polytechnique fédérale de Lausanne) and head of the Laboratory of Life Sciences Electronics located at EPFL's Lausanne campus.[1][2]

Professor
Carlotta Guiducci
Born1977 (age 46–47)
CitizenshipItaly
OccupationPrincipal investigator
AwardsIntel Early Career Faculty Honor Program Award
Academic background
EducationElectrical engineering
Electronic engineering
Alma materUniversity of Bologna
Academic work
DisciplineEngineering
Sub-disciplineBion-engineering
InstitutionsÉcole Polytechnique Fédérale de Lausanne (EPFL)
Main interestsAnalytical microsystems
Lab-on-a-chip devices
Portable DNA-based analytics
Websitehttps://clse.epfl.ch/

Career

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Guiducci studied electrical and electronics engineering at University of Bologna and received her Master's degree in 2001. In 2005, she gained a PhD degree in electrical engineering from Department of Electronics, Computer Sciences and Systems (DEIS) at University of Bologna for her work on electronic biosensors and the development of molecular sensors.[3] She joined the Nanobiophysics Laboratory at ParisTech as postdoctoral research fellow in 2005.[4] In 2007, she returned to University of Bologna as research fellow.[5][6]

In 2009, she became a faculty member of the Institute of Bioengineering at the School of Life Sciences at EPFL first as an Assistant Professor, and in 2018, she was promoted as Associate Professor.[1] She is the SwissUp Foundation chair, and the founder and head of Laboratory of Life Sciences Electronics.[7][8][9]

Research

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Guiducci's research centers on biomolecular analysis based on micro-fluidic systems,[10] and on novel personalized medicine approaches.[8][11] She is specialized in the integration and interfacing of analytic lab-on-a-chip devices that incorporate full-fledged laboratory equipment on a miniature scale.[12] She is developing miniaturized portable devices for DNA-based analytics,[11] high-throughput cytometry[13] and single-cell analysis.[14]

Selected works

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  • Stagni, Claudio; Guiducci, Carlotta; Benini, Luca; Ricco, Bruno; Carrara, Sandro; Samori, Bruno; Paulus, Christian; Schienle, Meinrad; Augustyniak, Marcin; Thewes, Roland (2006). "CMOS DNA Sensor Array with Integrated A/D Conversion Based on Label-Free Capacitance Measurement". IEEE Journal of Solid-State Circuits. 41 (12): 2956–2964. Bibcode:2006IJSSC..41.2956S. doi:10.1109/JSSC.2006.884867. S2CID 41863919.
  • Cagnin, Stefano; Caraballo, Marcelo; Guiducci, Carlotta; Martini, Paolo; Ross, Marty; Santaana, Mark; Danley, David; West, Todd; Lanfranchi, Gerolamo (2009). "Overview of Electrochemical DNA Biosensors: New Approaches to Detect the Expression of Life". Sensors. 9 (4): 3122–3148. Bibcode:2009Senso...9.3122C. doi:10.3390/s90403122. PMC 3348825. PMID 22574066.
  • Benini, L.; Farella, E.; Guiducci, C. (2006). "Wireless sensor networks: Enabling technology for ambient intelligence". Microelectronics Journal. 37 (12): 1639–1649. doi:10.1016/j.mejo.2006.04.021.
  • Guiducci, C. (2004). "DNA detection by integrable electronics". Biosensors and Bioelectronics. 19 (8): 781–787. doi:10.1016/S0956-5663(03)00266-5. PMID 15128096.
  • Stagni, Claudio; Guiducci, Carlotta; Benini, Luca; Ricco, Bruno; Carrara, Sandro; Paulus, Christian; Schienle, Meinrad; Thewes, Roland (2007). "A Fully Electronic Label-Free DNA Sensor Chip". IEEE Sensors Journal. 7 (4): 577–585. Bibcode:2007ISenJ...7..577S. doi:10.1109/JSEN.2007.891990. S2CID 32564939.
  • Cappi, Giulia; Spiga, Fabio M.; Moncada, Yessica; Ferretti, Anna; Beyeler, Michael; Bianchessi, Marco; Decosterd, Laurent; Buclin, Thierry; Guiducci, Carlotta (2015). "Label-Free Detection of Tobramycin in Serum by Transmission-Localized Surface Plasmon Resonance" (PDF). Analytical Chemistry. 87 (10): 5278–5285. doi:10.1021/acs.analchem.5b00389. PMID 25811093.
  • Lime, F.; Guiducci, C.; Clerc, R.; Ghibaudo, G.; Leroux, C.; Ernst, T. (2003). "Characterization of effective mobility by split C(V) technique in N-MOSFETs with ultra-thin gate oxides". Solid-State Electronics. 47 (7): 1147–1153. Bibcode:2003SSEle..47.1147L. doi:10.1016/S0038-1101(03)00049-2.

References

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  1. ^ a b "11 professors appointed at ETH Zurich and EPFL | ETH-Board". www.ethrat.ch. Retrieved 2020-10-01.
  2. ^ "Prof. Carlotta Guiducci". www.epfl.ch. Retrieved 2020-10-01.
  3. ^ Guiducci, C (2004-03-15). "DNA detection by integrable electronics". Biosensors and Bioelectronics. 19 (8): 781–787. doi:10.1016/S0956-5663(03)00266-5. PMID 15128096.
  4. ^ "NANOBIOPHYSICS LAB/ People". www.nbp.espci.fr. Retrieved 2020-10-02.
  5. ^ "CARLOTTA GUIDUCCI". 100 Women and Thousands More. Retrieved 2020-10-02.
  6. ^ Guiducci, Carlotta; Nardini, Christine (2008-04-01). "High parallelism, portability, and broad accessibility: Technologies for genomics". ACM Journal on Emerging Technologies in Computing Systems. 4 (1): 1–39. doi:10.1145/1330521.1330524. ISSN 1550-4832. S2CID 6216740.
  7. ^ "CLSE". www.epfl.ch. Retrieved 2020-10-02.
  8. ^ a b "Research at Swiss Up Chair on Engineering". www.epfl.ch. Retrieved 2020-10-02.
  9. ^ "Rencontre avec Carlotta Guiducci - Radio". Play RTS (in French). 22 March 2013. Retrieved 2020-10-02.
  10. ^ Thiriet, Pierre-Emmanuel; Pezoldt, Joern; Gambardella, Gabriele; Keim, Kevin; Deplancke, Bart; Guiducci, Carlotta (2020-03-20). "Selective Retrieval of Individual Cells from Microfluidic Arrays Combining Dielectrophoretic Force and Directed Hydrodynamic Flow". Micromachines. 11 (3): 322. doi:10.3390/mi11030322. ISSN 2072-666X. PMC 7143322. PMID 32244902.
  11. ^ a b Tenaglia, Enrico; Ferretti, Anna; Decosterd, Laurent A.; Werner, Dominique; Mercier, Thomas; Widmer, Nicolas; Buclin, Thierry; Guiducci, Carlotta (2018-06-30). "Comparison against current standards of a DNA aptamer for the label-free quantification of tobramycin in human sera employed for therapeutic drug monitoring". Journal of Pharmaceutical and Biomedical Analysis. 159: 341–347. doi:10.1016/j.jpba.2018.06.061. PMID 30025299. S2CID 51700744.
  12. ^ Guiducci, Carlotta (2017-07-27). "Integrated electrical sensing for high-throughput bioanalytics". 2017 IEEE International Conference on IC Design and Technology (ICICDT). Austin, TX, USA: IEEE. pp. 1–3. doi:10.1109/ICICDT.2017.7993520. ISBN 978-1-5090-4502-0. S2CID 44830895.
  13. ^ Rollo, Enrica; Tenaglia, Enrico; Genolet, Raphaël; Bianchi, Elena; Harari, Alexandre; Coukos, George; Guiducci, Carlotta (2017-08-15). "Label-free identification of activated T lymphocytes through tridimensional microsensors on chip". Biosensors and Bioelectronics. 94: 193–199. doi:10.1016/j.bios.2017.02.047. PMID 28284079.
  14. ^ Keim, Kevin; Rashed, Mohamed Z.; Kilchenmann, Samuel C.; Delattre, Aurélien; Gonçalves, António F.; Éry, Paul; Guiducci, Carlotta (2019-06-03). "On-chip technology for single-cell arraying, electrorotation-based analysis and selective release". Electrophoresis. 40 (14): 1830–1838. doi:10.1002/elps.201900097. ISSN 0173-0835. PMC 6771916. PMID 31111973.
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