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Nicholas Lowe

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Nicholas J Lowe (born 10 July 1944) is an English dermatologist who has published research into skin pharmacology, botulinum toxins, injectable filler and Lasers in cutaneous and cosmetic Surgery.[1]

Nicholas Lowe
Born (1944-07-10) July 10, 1944 (age 80)
England
EducationUniversity of Liverpool
OccupationDermatologist
TitleClinical Professor of Dermatology

He was president of the British Cosmetic Dermatology Group from 2013 to 2015.[2] He is a clinical professor of dermatology at UCLA School of Medicine, Los Angeles. He is a Fellow of the Royal College of Physicians, American Academy of Dermatology and American Society of Laser Medicine and Surgery.[3]

Education

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Lowe graduated from University of Liverpool School of Medicine,[4] England, in 1968. In 1975, he was awarded a Research Fellowship at the Scripps Research Institute where he worked with Professor Richard Stoughton, in skin pharmacology and percutaneous absorption. His doctoral MD research thesis described mechanisms and control of excessive epidermal cell growth.

In 1975, as a professor of dermatology at University of Wisconsin, he performed research on how ultraviolet light damages the skin and contributes to skin cancers.[5] He was subsequently appointed to Professor of Dermatology[6] at David Geffen School of Medicine at UCLA, Los Angeles, California, United States.

Research

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In 1980, he founded the largest psoriasis therapy centre in Southern California, the Dermatology Institute and Skin Care Center,[7] where he also conducted some of the first research studies on vitamin A derivatives for psoriasis, acne and other disfiguring skin diseases. He was appointed to the Medical Advisory Board of the National Psoriasis Foundation in the US.[citation needed]

In the 1980s, he conducted one of the first clinical research studies in psoriasis a completely new category of drugs for the treatment of psoriasis known as biologic drugs. These were drugs that were capable of targeting immunologic defects in psoriasis; new generations of these biological drugs are now used worldwide as biologic therapy for psoriasis, arthritis and related diseases.[8]

In 1980, he performed research on a category of the first new sunscreens that protected from long wave ultraviolet (or UVA) and UVB. He also confirmed that UVA was responsible for skin aging, skin cancer, unwanted pigmentation and skin sagging and during this research period he also proved the protectiveness of sunscreens against UVA damage in human studies.[9][10]

In the 1990s, he published research on the use of ultra-pulsed carbon dioxide lasers in dermatology,[11] which were developed and used to reduce skin aging, skin sagging, wrinkling and improve disfiguring scars.[12]

Lowe was the lead investigator in the first placebo control study of Botox for reducing forehead frown lines. At this time neither the dose nor was the safety of Botox was known. Lowe described the how to measure the improvement and using muscle recording electrodes and found the correct muscles to inject Botox. Together with dermatologist Dr Alastair Carruthers, he presented their early studies on the aesthetic use of Botox at the American Academy of Dermatology symposium.[13] He has also shown that Botox injections are an effective way of reducing and controlling the sweating for long periods of time. Pivotal publications on this include a British Medical Journal paper.[14]

Awards

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Research Publications and Resources

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Dr Lowe has written over 450 clinical and research papers and 19 books, sits on the editorial board of scientific journals and is a founding editor of the Journal of Cutaneous Laser Therapy.[18][19]

Books for the general public:

  • 1993 Managing Your Psoriasis[20]
  • 1999 Skin Secrets: The Medical Facts Versus The Beauty Fiction[21]
  • 2005 Away with Wrinkles: A Top Dermatologist's Secrets for a Younger Face[22]
  • 2007 The Wrinkle Revolution: Everywoman's Guide to a Younger Looking Skin[23]
  • 2016 Perfectly Clear, The Perfect Guide to Clear Skin[24]

Published medical books in chronological order are:

  • 1984-89 Models in Dermatology, Vol. I-IV Karger Publications[25][26][27][28]
  • 1989 Nonsteroidal Anti-inflammatory Agents, by Karger Publications[29]
  • 1990 Sunscreens: Development, Evaluation and Usage, Marcel Dekker;[30] 2nd ed. 1996
  • 1991 Sunscreens: A Physicians Guide. Marcel Dekker[31]
  • 1992 Practical Psoriasis Therapy, 2nd Edition, Mosby YearBook, New York.[32]
  • 1993 Managing Your Psoriasis, Master Media, New York[33]
  • 1995 Retinoids for the Clinician, Martin Dunitz, London;2nd ed., 1997[34]
  • 2000 Lasers in Cutaneous and Costmetic Surgery, Churchill Livingstone, NY, London.[35]
  • 2001 Facial Rejuvenation: Combination Minimally Invasive Treatments, Martin Dunitz, London[36]
  • 2003 Botox: Aesthetic Conditions[37]
  • 2003 Psoriasis - A Patient Guide, Martin Dunitz, London 3rd edition. Highly commended, BMA Medical Book Competition 2004[38]

References

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  1. ^ "Meet Dr Nick Lowe". Aesthetics Insider.
  2. ^ "Dr Nick Lowe joins Aesthetics editorial board". Aesthetics. Retrieved 11 December 2022.
  3. ^ "Meet Dr Nick Lowe". Aesthetic Medicine.
  4. ^ "Nicholas Charles LOWE". General Medical Council.
  5. ^ Lowe, NJ; Stoughton, RB (February 1977). "Essential fatty acid deficient hairless mouse: a model of chronic epidermal hyperproliferation". The British Journal of Dermatology. 96 (2): 155–62. doi:10.1111/j.1365-2133.1977.tb12537.x. PMID 843450. S2CID 2486355.
  6. ^ "Spotlight on: Nicholas Lowe, MB, ChB, MD, FRCP". The Dermatologist. Dermatology Learning Network.
  7. ^ "Clinical Science Institute - Dermatology Institute & Skin Care Center". www.discc.com. Retrieved 21 January 2018.
  8. ^ Lowe, N J (28 March 1987). "Phototherapy and dithranol treatment of psoriasis". BMJ. 294 (6575): 839. doi:10.1136/bmj.294.6575.839. PMC 1245892. PMID 3105768.
  9. ^ Sunscreens: Development, Evaluation, and Regulatory Aspects. "M Decker", Google Books.
  10. ^ Physician's Guide to Sunscreens. "Dekker", Google Books.
  11. ^ LOWE, NICHOLAS J.; LASK, GARY; GRIFFIN, MOLLY E.; MAXWELL, ANNE; LOWE, PHILIPPA; QUILADA, FLORIZZA (December 1995). "Skin Resurfacing with the Ultrapulse Carbon Dioxide Laser". Dermatologic Surgery. 21 (12): 1025–1029. doi:10.1111/j.1524-4725.1995.tb00552.x. PMID 7496669. S2CID 23913846.
  12. ^ LOWE, NICHOLAS J.; LASK, GARY; GRIFFIN, MOLLY E. (December 1995). "Laser Skin Resurfacing". Dermatologic Surgery. 21 (12): 1017–1019. doi:10.1111/j.1524-4725.1995.tb00550.x. S2CID 30122352.
  13. ^ "In 1996 at the annual meeting of The American Academy of Dermatology in Washington, a presentation by dermatologist Dr. Nicholas Lowe showed that BOTOX® was useful for improving facial expression lines". Dermatology Associates of Atlanta. 4 June 2013. Retrieved 8 July 2015.
  14. ^ Naumann, M; Lowe, N J (15 September 2001). "Botulinum toxin type A in treatment of bilateral primary axillary hyperhidrosis: randomised, parallel group, double blind, placebo controlled". BMJ. 323 (7313): 596–599. doi:10.1136/bmj.323.7313.596. PMC 55572. PMID 11557704.
  15. ^ "Dr Nicholas James LOWE". IMCAS.
  16. ^ "Dr Nicholas James LOWE". IMCAS.
  17. ^ "Meet Dr Nicck Lowe". Aesthetics Insider.
  18. ^ P Lask, Nicholas J Lowe, Gary (January 1999). "Editorial". Journal of Cosmetic and Laser Therapy. 1 (1): 1–2. doi:10.1080/14628839950517020.
  19. ^ Lowe, Nicholas. "Lowe". Research Gate.
  20. ^ Lowe, Nicholas J. (1993). Managing your psoriasis. New York: MasterMedia. ISBN 978-0942361841.
  21. ^ Sellar, Nicholas Lowe, Polly (1999). Skin secrets : the medical facts versus the beauty fiction. London: Collins & Brown. ISBN 1855856654.{{cite book}}: CS1 maint: multiple names: authors list (link)
  22. ^ Lowe, Nick (2005). Away with wrinkles : the essential guide to a younger-looking face. New York: Marlowe & Co. ISBN 1569244588.
  23. ^ Lowe, Nick (2007). The wrinkle revolution : a top dermatologist's latest secrets (Rev.. ed.). London: Kyle Cathie Ltd. ISBN 978-1856267717.
  24. ^ Lowe, Nick (10 March 2016). Perfectly Clear. Troubador Publishing. ISBN 978-1785890833.
  25. ^ Models in Dermatology, Vol. 1. Karger. ISBN 978-3-8055-3945-6.
  26. ^ Models in Dermatology, Vol. 2. Karger. ISBN 978-3-8055-3947-0.
  27. ^ Models in Dermatology, Vol. 3. Karger. 1987. ISBN 978-3-8055-4239-5.
  28. ^ Models in Dermatology, Vol. 4. Karger. 1985. ISBN 978-3-8055-4761-1.
  29. ^ Nonsteroidal anti-inflammatory drugs. "Karger", Google Books.
  30. ^ Sunscreens: Development, Evaluation, and Regulatory Aspects. "M Decker", Google Books.
  31. ^ Physician's Guide to Sunscreens. "Dekker", Google Books.
  32. ^ Lowe, Nicholas J. Lowe (1993). Practical psoriasis therapy (2nd. ed.). St. Louis: Mosby-Year Book. ISBN 9780801671814.
  33. ^ Managing Your Psoriasis. "Master Media", Google Books.
  34. ^ Psoriasis: Retinoids, Second Edition. "Taylor & Francis", Google Books.
  35. ^ Lowe, Gary P. Lask; Nicholas J. (2000). Lasers in cutaneous and cosmetic surgery (1st ed.). Philadelphia [u.a.]: Churchill Livingstone. ISBN 9780443076398.{{cite book}}: CS1 maint: multiple names: authors list (link)
  36. ^ al.], Nicholas J. Lowe ... [et (2001). Textbook of facial rejuvenation : the minimally invasive combination approach (Repr. ed.). London: Martin Dunitz. ISBN 9781841840956.
  37. ^ Botox: Aesthetic Conditions. "Taylor & Francis", Google Books.
  38. ^ Psoriasis: A Patient's Guide, Third Edition. "Taylor & Francis", Google Books.
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