Enterovirus 5′ cloverleaf cis-acting replication element

The Enterovirus 5′ cloverleaf cis-acting replication element is an RNA element found in the 5′ UTR of Enterovirus genomes. The element has a cloverleaf like secondary structure and is known to be a multifunctional cis-acting replication element (CRE), required for the initiation of negative strand RNA synthesis.[1]

Enterovirus 5′ cloverleaf cis-acting replication element
Predicted secondary structure and sequence conservation of Entero_5_CRE
Identifiers
SymbolEntero_5_CRE
RfamRF00386
Other data
RNA typeCis-reg
Domain(s)Viruses
SOSO:0000233
PDB structuresPDBe

See also

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References

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  1. ^ Barton DJ, O'Donnell BJ, Flanegan JB (March 2001). "5′ cloverleaf in poliovirus RNA is a cis-acting replication element required for negative-strand synthesis". The EMBO Journal. 20 (6): 1439–1448. doi:10.1093/emboj/20.6.1439. PMC 145522. PMID 11250909.
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