Esfandiari (Persian: اسفندیاری, Esfandiyārī, meaning related to Esfandiyār) refer to the following:
- Esfandiari, Iran
- Ali Esfandiari, known as Nima Yooshij
- Antonio Esfandiari, professional poker player and magician
- Haleh Esfandiari
- Soraya Esfandiari
- Tim Esfandiari, known as Esfand