Esperance may refer to:
- Esperance (town), New York
- Esperance (village), New York
- Esperance, Quartier Militaire (village), Quartier Militaire, Moka, Mauritius
- Esperance, Washington
- Esperance, Western Australia
- Goldfields–Esperance, a large region in Western Australia
- Shire of Esperance, a local government area in Western Australia
- Cape Esperance, Solomon Islands
- Battle of Cape Esperance, a WWII naval battle
- Exuperantia (Esperance), French saint
- HMS Esperance, two ships of the Royal Navy