Syndetin is a protein that in humans is encoded by the VPS50 gene. It is a component of the EARP complex that is involved in endocytic recycling.[5]

VPS50
Identifiers
AliasesVPS50, CCDC132, VPS54L, FLJ20097 / CCDC132, EARP/GARPII complex subunit, VPS50 subunit of EARP/GARPII complex, NEDMSC
External IDsOMIM: 616465; MGI: 1920538; HomoloGene: 11498; GeneCards: VPS50; OMA:VPS50 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001257998
NM_017667
NM_024553

NM_001167750
NM_001167751
NM_024260

RefSeq (protein)

NP_001244927
NP_060137
NP_078829

NP_001161222
NP_001161223
NP_077222

Location (UCSC)Chr 7: 93.23 – 93.36 MbChr 6: 3.5 – 3.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

edit
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000004766Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001376Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Schindler C, Chen Y, Pu J, Guo X, Bonifacino JS (2015). "EARP is a multisubunit tethering complex involved in endocytic recycling". Nature Cell Biology. 17 (5): 639–50. doi:10.1038/ncb3129. PMC 4417048. PMID 25799061.