DescriptionELMO1 (CED-12) and DOCK2 (CED-5) ternary complex in apoptosis.jpg
English: (A) A simple graphical representation of the protein domains for DOCK2 (mammalian homolog to CED-5) and ELMO1 (mammalian homolog for CED-12). On DOCK2/CED-5, the SH3-domain that binds to ELMO1/CED-12 is shown as a blue rectangle. On ELMO1, Proline-Rich regions are in light-blue. These indicate the regions in which ELMO1/CED-12 and DOCK2/CED-5 interact when forming a complex.
(B) A crystalline 3D-representation of the heterodimer structure between DOCK2/CED-5 and ELMO1/CED-12. On the right is the same crystalline structure rotated 90°.
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