Galene can refer to:
- Galene (mythology), one of the Nereids
- 427 Galene, a main belt asteroid
- Galene (crab), a genus of crabs
- Galene, a genus of Algae,
- Galene or Galène, a free and open source videoconferencing suite.
See also
edit- Galen (disambiguation)
- Galena (disambiguation)
- Galina, a given name