Giant Killers or Giant Killer may refer to:
Entertainment
edit- Giant Killers (EP), a 2017 EP by BiSH
- Giant Killers (video game), a 2001 video game
- "Giant Killer" (story), a 1945 short story by A. Bertram Chandler
- The Giant Killer, the British title of the 2013 American film Jack the Giant Killer
- Giantkiller, an American comic book series
Sports
edit- Giant killers (sports), an underdog team or person that defeats an expected winner
- 1967 Oregon State Beavers football team, an American college football team nicknamed "Giant Killers" for their performance
Other uses
edit- Giant Killer (call sign), an American military aviation call sign