Golovachev, Golovachov, Golovachyov (feminine: Golovachova) is a Russian family name, a patronymic from the nickname Golovach ("big headed"). It is also the name of a Russian noble family raising to prominence in the 16th century.
The surname may refer to:
- Vasili Golovachov
- Aleksandr Golovachev, Soviet colonel, twice Hero of the Soviet Union
- Pavel Golovachev, Soviet ace, twice Hero of the Soviet Union
- Nikolai Nikitich Golovachev (born 1823, died 1887), a Russian general, participant in the Caucasian War and Turkestan campaigns