Herzegovina uprising or Herzegovinian uprising may refer to:
- Herzegovina uprising (1596–97), fought by Serbs in Herzegovina against the Ottoman Empire, 1596–1597
- Herzegovina uprising (1852–62), fought by Serbs in Herzegovina against the Ottoman Empire, 1852–1862
- Herzegovina uprising (1875–77), fought by Serbs in Herzegovina against the Ottoman Empire, 1875–1877
- June 1941 uprising in eastern Herzegovina, fought by Serbs in eastern Herzegovina against Ustaše in 1941