Homoisocitric acid is an isomer of homocitric acid in which the hydroxyl is on the 2 position.[1] It is an intermediate in the α-aminoadipate pathway of lysine biosynthesis where it is produced by homocitrate synthase and is a substrate for homoaconitase.

Homoisocitric acid
Names
Preferred IUPAC name
1-Hydroxybutane-1,2,4-tricarboxylic acid
Other names
3-Carboxy-2-hydroxyadipic acid
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
KEGG
  • InChI=1S/C7H10O7/c8-4(9)2-1-3(6(11)12)5(10)7(13)14/h3,5,10H,1-2H2,(H,8,9)(H,11,12)(H,13,14)
    Key: OEJZZCGRGVFWHK-UHFFFAOYSA-N
  • InChI=1/C7H10O7/c8-4(9)2-1-3(6(11)12)5(10)7(13)14/h3,5,10H,1-2H2,(H,8,9)(H,11,12)(H,13,14)
    Key: OEJZZCGRGVFWHK-UHFFFAOYAM
  • O=C(O)CCC(C(=O)O)C(O)C(=O)O
Properties
C7H10O7
Molar mass 206.150 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Homoisocitrate is an anion, salt, or ester of homoisocitric acid.

See also

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References

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  1. ^ "Homoisocitric Acid". U.S. National Library of Medicine; National Center for Biotechnology Information.