The hotcross bun sign is a radiologic sign observed on transverse T2-weighted magnetic resonance (MR) images of the brain, describing a cross-shaped (or cruciform) hyperintensity within the pons. This sign is most commonly associated with the cerebellar subtype of multiple system atrophy (MSA-c)[1]. It is also associated with spinocerebellar ataxia, progressive multifocal leukoencephalopathy, paraneoplastic cerebellar degeneration, and Creutzfeldt-Jakob disease[2].
References
edit- ^ Shrivastava, Arpan (2007). "The Hot Cross Bun Sign". Radiology. 245 (2): 606–607. doi:10.1148/radiol.2452041856. ISSN 0033-8419.
- ^ Johnson, Ryan; Lausch, John; Degenstein, Dakota; Reznikov, Boris (2024). ""One a penny, two a penny", I saw the hot cross bun sign"". Clinical Imaging. 114. doi:10.1016/j.clinimag.2024.110251. ISSN 0899-7071. PMID 39153381.