HNLMS Isaac Sweers (Dutch: Hr.Ms. or Zr.Ms. Isaac Sweers) may refer to following ships of the Royal Netherlands Navy:
- HNLMS Isaac Sweers (1940), a Gerard Callenburgh-class destroyer
- HNLMS Isaac Sweers (F814), a Van Speijk-class frigate
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.